Myeloid/lymphoid neoplasm with eosinophilia and FIP1L1-PDGFRA rearrangement associated with peripheral T-lymphoma NOS ¿Is it probable?
Vol. 26 No. 3 (2022), Brief communications
Vol. 26 No. 3 (2022)

Myeloid/lymphoid neoplasm with eosinophilia and FIP1L1-PDGFRA rearrangement associated with peripheral T-lymphoma NOS ¿Is it probable?

Brief communications
https://doi.org/10.48057/hematologa.v26i3.481
Published 2023-01-16
Héctor Chiang
Hospital José Carrasco Arteaga de Cuenca
Patricio González
Hospital José Carrasco Arteaga de Cuenca
Pablo Farfán
Revista Hematología
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Keywords

eosinophilia
T lymphoma
PDGFRA

How to Cite

Chiang, H., González , P. ., & Farfán, P. (2023). Myeloid/lymphoid neoplasm with eosinophilia and FIP1L1-PDGFRA rearrangement associated with peripheral T-lymphoma NOS ¿Is it probable?. Journal of Hematology, 26(3), 84–88. https://doi.org/10.48057/hematologa.v26i3.481
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Abstract

We present the case of a male patient with myeloid/ lymphoid neoplasm with eosinophilia (NML-eo) and PDGFRA rearrangement, with a history of peripheral T-cell lymphoma (LT-NOS) and hypereosinophilia. NML-eo and PDGFRA rearrangement arise from a pluripotent hematopoietic progenitor cell, which generates both myeloid and lymphoid differentiation lineages. The fusion gene can be expressed in eosinophils, neutrophils, mast cells, T cells, B cells and monocytes. Is the association between T NOS and NML-eo lymphoma with PDGFRA possible?

https://doi.org/10.48057/hematologa.v26i3.481
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