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Abstract
The detection of a vertebral fracture in a patient with monoclonal gammopathy requires a multidisciplinary evaluation, in order to make an adequate therapeutic decision. Here we present the case of a female patient with a diagnosis of plasma cell dyscrasia referred to oncological treatment.
References
2. Rajkumar S et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014; 14 (12): e538-e458.
3. Perez-Persona E et al. New criteria to identify risk of progression in monoclonal gammopathy of uncertain significance and smoldering multiple myeloma based on multiparameter flow cytometry analysis of bone marrow plasma cells. Blood. 2007; 110: 2584-2592.
4. Pianko et al. Whole body low dose CT vs whole body X ray. Clin Cancer Res. 2014; 20(23): 5888-97.
5. Cavo et al. Role of the 18F-FDG PET/TC in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International Myeloma Working Group. Lancet Oncol. 2017; 18: e206-17.
6. Dimoupoulos et al. Role of Magnetic Resonance Imaging in the management of patients with multipe myeloma; a consensus statement. J Clin Oncol. 2015; 33:657-664.
7. Chaudhry et al. Monoclonal gammopathy associated peripheral neuropathy: diagnosis and management. Mayo Clin Proc. 2017; 92(5): 838- 850.
8. Dispenzieri A et al. POEMS syndrome: definitions and long-term outcome. Blood. 2003; 101: 2496-2501.
9. Yeung et al. The clinical spectrum of peripheral neuropathies associated with benign monoclonal IgM, IgG and IgA paraproteinaemia, comparative clinical, immunological and nerve biopsy findings. J Neurol. 1991; 238(7).383-391.
10. Bleasel et al. IgG monoclonal paraproteinaemia and peripheral neuropathy. J Neurol Neurosurg Psychiatry. 1993; 56(1)52-57.
11. Stork et al. Prevalence, specificity and functionality of anti-ganglioside antibodies in neuropathy associated with IgM monoclonal gammopathy. J Neuroinmunolol. 2014; 268(1) 89-94.
12. Sigrun Thorsteinsdottir. Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study. Blood Adv. 2017 Dec 26; 1(27): 2790- 2798.
13. J M Piot. Factors associated with an increased risk of vertebral fracture in monoclonal gammopathies of undetermined significance. Blood Cancer J. 2015 Aug; 5(8): e345.
14. DrakenM. Unveiling skeletal fragility in patients diagnosed with MGUS: no longer a condition of undetermined significance?. J of Bone and Mineral Research. 2014; 29(12) 2529-2533.
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